Evaluation of antitumour activity of Calotropis gigantea L. root bark against Ehrlich ascites carcinoma in Swiss albino mice
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منابع مشابه
Antitumor Activity and In Vivo Antioxidant Status of Mucuna Pruriens (Fabaceae) Seeds against Ehrlich Ascites Carcinoma in Swiss Albino Mice
The aim of the present study is to evaluate the antitumor effect and antioxidant role of Mucuna pruriens (Family: Fabaceae) against EAC bearing Swiss albino mice. The effect of methanol extract of Mucuna pruriens (MEMP) on tumor growth and hosts survival time was studied by the following parameters: tu-mor volume, packed cell volume, viable and non-viable cell count and life span of the host. M...
متن کاملInhibition of Ehrlich ascites carcinoma by Manilkara zapota L. stem bark in Swiss albino mice.
OBJECTIVE To evaluate the antitumor activity of Manilkara zapota (M. zapota) L. stem bark against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. METHODS The in vivo antitumour activity of the ethyl acetate extract of stem bark of M. zapota L. (EASM) was evaluated at 50, 100 and 200 mg/kg bw against EAC using mean survival time. After administration of the extract of M. zapota, viable E...
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Drug delivery systems such as nanoparticles are used to improve the pharmacological and therapeutic properties of anticancer drugs. In this study, a biodegradable polymer chitosan (CS) was used for delivery of cyclophosphamide (CP). Cyclophosphamide loaded chitosan nanoparticles (CP-CS-NPs) were prepared by ion cross-linking to form a uniform particle size of 186.53 ±1.865 nm with 78±2.67 % ent...
متن کاملInsecticidal Activity of Root Bark of Calotropis gigantea L. Against Tribolium castaneum (Herbst)
The residual film toxicity, fumigant toxicity and repellent effect of methanol extract of root bark of Calotropis gigantea (Linn) and its chloroform and petroleum ether (40-60°C) soluble fractions were evaluated against several inster of larvae and adult of Tribolium castaneum. In residual film toxicity, methanol extract and its chloroform and petroleum ether fractions showed insecticidal activ...
متن کاملEvaluation of In vivo Anticancer Activity of Scaevola taccada Roxb against Ehrlich Ascites Carcinoma in Swiss Albino Mice
Objective: The present study was carried out to evaluate the anticancer property of ethanol extract of Scaevola taccada leaves against Ehrlich ascites carcinoma in Swiss albino mice. Materials and Methods: The leaves powder was subjected to continuous hot extraction using ethanol and cold maceration by water to get Ethanol and Aqueous extracts, respectively. Identification of the chemical const...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2011
ISSN: 1995-7645
DOI: 10.1016/s1995-7645(11)60194-6